Immunity to Protozoan Parasites

Ups and downs of mucosal cellular immunity against protozoan parasites.

CD40-CD40L Interaction in Immunity Against Protozoan Infections

Activation of the immune system against protozoan infections relies particularly on two specific signals provided by cognate interaction of T cells with antigen presenting cells (APCs). The first signal is attributed to binding of the T-cell receptor (TCR) to peptide/MHC complexes on the surface of APCs, whereas the second signal is triggered through binding of several costimulatory molecules o...

B-Cell Response during Protozoan Parasite Infections

In this review, we discuss how protozoan parasites alter immature and mature B cell compartment. B1 and marginal zone (MZ) B cells, considered innate like B cells, are activated during protozoan parasite infections, and they generate short lived plasma cells providing a prompt antibody source. In addition, protozoan infections induce massive B cell response with polyclonal activation that leads...

Micro-cantilevered MEMS Biosensor for Detection of Malaria Protozoan Parasites

In this paper, the presented work aims to provide a designed model based on Finite element method for detection of Malaria protozoan parasites. Micro-cantilevers are next generation highly efficient biosensors for detection and prevention of any disease. Here, an E-shaped model for micro cantilevered biosensor is designed using COMSOL Multiphysics specifically for detection of Malaria. Microcan...

Direct Molecular Detection and Phylogenetic Tree Analysis of Gastrointestinal Protozoan Parasites (Giardia lamblia, Entamoeba histolytica, Cryptosporidium parvum) from Diarrhea Infection in Kut City of Iraq: A Short Communication

Background: The intestinal tract of human can be infected by protozoan parasites. In this short communication, the stool samples were collected from patients with diarrhea referred to Kut hospital, Iraq, and then the parasites (Giardia lamblia, Entamoeba histolytica, Cryptosporidium parvum) were considered for molecular identification. Methods: Stool samples were collected from 69 patients wit...

HIV Protease Inhibitors: Effect on the Opportunistic Protozoan Parasites

The impact of highly active antiretroviral therapy (HAART) in the natural history of AIDS disease has been allowed to prolong the survival of people with HIV infection, particularly whose with increased HIV viral load. Additionally, the antiretroviral therapy could exert a certain degree of protection against parasitic diseases. A number of studies have been evidenced a decrease in the incidenc...